KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5C
All Species:
39.09
Human Site:
S260
Identified Species:
61.43
UniProt:
O60282
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60282
NP_004513.1
957
109495
S260
K
N
I
N
K
S
L
S
A
L
G
N
V
I
S
Chimpanzee
Pan troglodytes
XP_525938
860
98662
S235
K
T
I
K
N
T
V
S
V
N
L
E
L
T
A
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
Q234
Y
N
D
S
N
N
S
Q
S
L
Q
Q
Q
L
T
Dog
Lupus familis
XP_533351
955
109129
S259
K
N
I
N
K
S
L
S
A
L
G
N
V
I
S
Cat
Felis silvestris
Mouse
Mus musculus
P28738
956
109222
S260
K
N
I
N
K
S
L
S
A
L
G
N
V
I
S
Rat
Rattus norvegicus
Q6QLM7
1027
116897
S260
K
N
I
N
K
S
L
S
A
L
G
N
V
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
L258
A
K
N
I
N
K
S
L
S
A
L
G
N
V
I
Chicken
Gallus gallus
Q90640
1225
138905
L271
I
N
R
G
L
L
C
L
G
N
V
I
S
A
L
Frog
Xenopus laevis
Q91784
1226
138905
L270
I
N
R
G
L
L
C
L
G
N
V
I
S
A
L
Zebra Danio
Brachydanio rerio
NP_001116747
985
113653
S259
K
N
I
N
K
S
L
S
A
L
G
N
V
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
S266
K
N
I
N
K
S
L
S
A
L
G
N
V
I
S
Honey Bee
Apis mellifera
XP_395236
988
112484
S270
K
N
I
N
K
S
L
S
A
L
G
N
V
I
S
Nematode Worm
Caenorhab. elegans
P34540
815
91875
T214
S
H
S
V
F
L
I
T
V
K
Q
E
H
Q
T
Sea Urchin
Strong. purpuratus
P35978
1031
117504
S258
K
N
I
N
K
S
L
S
A
L
G
N
V
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
S263
K
K
I
N
K
S
L
S
A
L
G
M
V
I
N
Conservation
Percent
Protein Identity:
100
89.8
85.5
98.3
N.A.
98
69.8
N.A.
75.2
26.3
24.8
76.8
N.A.
62
63.2
45.3
61.4
Protein Similarity:
100
89.8
86.4
98.9
N.A.
99.1
81.6
N.A.
86.4
45.3
45.5
86.9
N.A.
77.6
77.9
61.3
74.7
P-Site Identity:
100
20
13.3
100
N.A.
100
100
N.A.
0
6.6
6.6
100
N.A.
100
100
0
100
P-Site Similarity:
100
46.6
46.6
100
N.A.
100
100
N.A.
13.3
6.6
6.6
100
N.A.
100
100
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
60
7
0
0
0
14
7
% A
% Cys:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
14
0
0
0
0
14
0
60
7
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
14
0
67
7
0
0
7
0
0
0
0
14
0
60
7
% I
% Lys:
67
14
0
7
60
7
0
0
0
7
0
0
0
0
0
% K
% Leu:
0
0
0
0
14
20
60
20
0
67
14
0
7
7
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
74
7
60
20
7
0
0
0
20
0
54
7
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
14
7
7
7
0
% Q
% Arg:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
7
7
0
60
14
67
14
0
0
0
14
0
54
% S
% Thr:
0
7
0
0
0
7
0
7
0
0
0
0
0
7
14
% T
% Val:
0
0
0
7
0
0
7
0
14
0
14
0
60
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _